Designing selective PARP inhibitors
A Potent and Selective PARP11 Inhibitor Suggests Coupling between Cellular Localization and Catalytic Activity. Ilsa T. Kirby, Ana Kojic and Moriah R. Arnold, Ann-Gerd Thorsell, Tobias Karlberg, Anke Vermehren-Schmaedick, Raashi Sreenivasan, Carsten Schultz, Herwig Schüler, and Michael S. Cohen. Cell Chemical Biology, 25, 1–7 (2018). PDF
Kirby, I.T., Morgan, R.K., and Cohen, M.S. “A simple, sensitive, and generalizable plate assay for screening PARP inhibitors,” Methods in Molecular Biology, in press (2018).
Morgan, R.K., Carter-O'Connell, I.O., and Cohen, M.S. "Selective inhibition of PARP10 using a chemical genetics strategy," Bioorganic Medicinal Chemistry Letters, 25, 4770 (2015). PDF
Kirby, I.T., Morgan, R.K., and Cohen, M.S. “A simple, sensitive, and generalizable plate assay for screening PARP inhibitors,” Methods in Molecular Biology, in press (2018).
Morgan, R.K., Carter-O'Connell, I.O., and Cohen, M.S. "Selective inhibition of PARP10 using a chemical genetics strategy," Bioorganic Medicinal Chemistry Letters, 25, 4770 (2015). PDF
