Cohen Lab
  • Home
  • Research
    • Quantifying NAD+ in cells
    • Designing selective PARP inhibitors
    • Exploring the role of PARPs in neurodevelopment
    • Identifying direct targets of PARPs
  • Team
    • Current Members
    • Past Members
    • Fun
  • Publications
  • News
  • Around the Lab
  • Resources
  • Contact
  • Lab Resources

Designing selective PARP inhibitors

A Potent and Selective PARP11 Inhibitor Suggests Coupling between Cellular Localization and Catalytic Activity. Ilsa T. Kirby, Ana Kojic and Moriah R. Arnold, Ann-Gerd Thorsell, Tobias Karlberg, Anke Vermehren-Schmaedick, Raashi Sreenivasan, Carsten Schultz, Herwig Schüler, and Michael S. Cohen. Cell Chemical Biology, 25, 1–7 (2018). PDF
​
Kirby, I.T., Morgan, R.K., and Cohen, M.S. “A simple, sensitive, and generalizable plate assay for screening PARP inhibitors,” Methods in Molecular Biology, in press (2018).  

​Morgan, R.K., Carter-O'Connell, I.O., and Cohen, M.S. "Selective inhibition of PARP10 using a chemical genetics strategy," Bioorganic Medicinal Chemistry Letters, 25, 4770 (2015). PDF
Powered by Create your own unique website with customizable templates.
  • Home
  • Research
    • Quantifying NAD+ in cells
    • Designing selective PARP inhibitors
    • Exploring the role of PARPs in neurodevelopment
    • Identifying direct targets of PARPs
  • Team
    • Current Members
    • Past Members
    • Fun
  • Publications
  • News
  • Around the Lab
  • Resources
  • Contact
  • Lab Resources