Cohen Lab
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    • Quantifying NAD+ in cells
    • Designing selective PARP inhibitors
    • Exploring the role of PARPs in neurodevelopment
    • Identifying direct targets of PARPs
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The Latest and Greatest


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Our newest work is out in JACS now! Here, we describe clickable, diazirine NAD analogs for labeling and identification of NAD binding proteins in a cellular context. Read more here


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Kelsie defends her thesis!
You can read all about here work in her recent eLife paper here. Kelsie will be moving to UC Santa Cruz this year on the IRACDA fellowship and will be joining the lab of Dr. Seth Rubin.
All the best to Dr. Rodriguez in her future endeavors. 


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We have new students! Welcome Danny Bejan (Left), who will be focusing on development of novel PARP inhibitors, and Ivan R. Siordia (Right), who will be co-mentored by Dr. Liman Zhang and focusing on the structural biology of the PARP family. Welcome!

New review! Michael Cohen takes a look at the role of PARPs in compartmentalized NAD+ synthesis and consumption in his new Genes and Development Review. Check out Interplay between compartmentalized NAD+ synthesis and consumption: a focus on the PARP family
February 6, 2020
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Hot off the presses at Cell Chemical Biology: A Potent and Selective PARP11 Inhibitor Suggests Coupling between Cellular Localization and Catalytic Activity. Check it out to see what our senior grad student Ilsa has been up to for the last two years
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Another September article for the Cohen lab: check out "Combining Chemical Genetics with Proximity-Dependent Labeling Reveals Cellular Targets of Poly(ADP-ribose) Polymerase 14 (PARP14)" in ACS Chemical Biology!
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A new review on PARP inhibitors by Ilsa and Mike has just gone online! Part of the Current Topics in Microbiology and Immunology book series from Springer.
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September 22nd, 2018

Our senior grad student Ilsa has accepted a post-doc position in the Shokat lab at UCSF! Ilsa plans to defend her dissertation (which she promises to start writing soon, probably) in January 2019 and start at UCSF in the spring where she will continue her work in Chemical Biology.
August 6th, 2018

Former Cohen lab research technician Madison is headed to the Kacar lab at the University of Arizona. There she will be conducting research in synthetic Biology, molecular evolution, and astrobiology. She will continue on at UA for her PhD in Cellular and Molecular Biology.
February 18th, 2018

A review on ADP-ribosylation is out from Mike and Paul Chang! Check it out in the latest issue of Nature Chemical Biology.
February 14th 2018
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  • Home
  • Research
    • Quantifying NAD+ in cells
    • Designing selective PARP inhibitors
    • Exploring the role of PARPs in neurodevelopment
    • Identifying direct targets of PARPs
  • Team
    • Current Members
    • Past Members
    • Fun
  • Publications
  • News
  • Around the Lab
  • Resources
  • Contact
  • Lab Resources